Features of national account of donor platelets collection

Based on the analysis of the practice of collection and the volume of units of donor red blood cells, plasma and cryoprecipitate in 13 Russian blood service organizations, it was established:
- volumes of units of 9 received types of erythrocytes differ significantly: H-test of Kruskal-Wallis – 32,071 with a critical value of 15,507 (p < 0,001);
- the volume of red blood cells suspension exceeds the volume of red blood cells suspension mass by 28,8% (p = 0,004);
- removal of the buffy-coat reduces the volume of red blood cells suspension suspension – by 14,8% (p = 0,002);
- leukodepletion does not reduce the volume of red blood cells suspension and mass;
- the volume of washed red blood cells is the most variable (median absolute deviation = 33), since it is determined by an arbitrary amount of saline added to the final product;
- pathogen inactivation does not affect the plasma volume, which allows us to recommend the production of pathogen-reduced cryoprecipitate;
- there is no unequivocal qualification of cryosupernatant plasma as a therapeutic product or a vastage in cryoprecipitate production (out of 12 organizations collected cryoprecipitate, 5 indicated the preparation of cryosupernatant plasma);
- 3 out of 13 participants in the study have already implemented the production of pooled cryoprecipitate – a technology that significantly reduces labor costs and 92% – unproductive consumption of the medical product (p < 0,001);
- the current system for accounting for the volume of red blood cells and plasma collection does not allow estimating the number of prepared therapeutic units;
- it is proposed to account donor red blood cells, plasma for transfusion and cryoprecipitate in units, and plasma for the production of medicines – in liters.

Authors: Zhiburt E. B. [15] Averyanov E. G. [6] Shestakov E. A. [6] Pokhabov D. S. [1]

Tags: account2 blood8 blood collection5 plasma3 red blood cells3 unit4 volume4